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The generic name of Paxil is paroxetine hydrochloride; an orally administered psychotropic drug. It is an odorless, off-white powder and with a solubility of 5.4 mg/ml in water. It is available in tablet and suspension form that the patient can choose from 10 mg-yellow, 20 mg-pink, 30 mg-blue and 40 mg-green. The suspension form of this drug that contains ml of orange-colored liquid that is equal to 10 mg of Paxil.
This drug is indicated for treatment of major depressive disorder and its major depressive episode was established in 6- week controlled trials of outpatient whose diagnoses corresponded mostly closely to DSM-III category of major depressive disorder. This category indicates episodes a prominent and relatively persistent depressed or dysphoric mood that usually interferes with daily functioning and should include 4 of the following symptoms: increased fatigue, change in sleep, change in appetite, loss of interest in usual activities or decrease in sexual drive, feelings of guilt or worthlessness, suicide attempt and slowed thinking or impaired concentration.
Paxil is also indicated for the treatment of patient having obsessions and compulsions in patient’s with obsessive compulsive disorder as defined in the DSM-IV. The obsessions and compulsions may interfere with social and occupational functioning, time consuming and cause marked distress. The efficacy of this drug is established in two 12- week trials with patient’s having obsessive compulsive disorder and these disorder is characterized by persistent and recurrent ideas, thoughts, images and impulses that are ego-dystonic and / or repetitive, purposeful and intentional behaviors that are recognized by the person as excessive or unreasonable.
PAXIL is also indicated for the treatment of panic disorder, with or without agoraphobia, as defined in DSM-IV. Panic disorder is characterized by the occurrence of unexpected panic attacks and associated concern about having additional attacks, a significant change in behavior related to the attacks, worry about the implications or consequences of the attacks and significant change in behavior related to the attacks.
Panic disorder is characterized by recurrent unexpected panic attacks, i.e., a discrete period of intense fear or discomfort in which 4 (or more) of the following symptoms develop abruptly and reach a peak within 10 minutes: (1) palpitations, pounding heart, or accelerated heart rate; (2) sweating; (3) trembling or shaking; (4) sensations of shortness of breath or smothering; (5) feeling of choking; (6) chest pain or discomfort; (7) nausea or abdominal distress; (8) feeling dizzy, unsteady, lightheaded, or faint; (9) derealization (feelings of unreality) or depersonalization (being detached from oneself); (10) fear of losing control; (11) fear of dying; (12) paresthesias (numbness or tingling sensations); (13) chills or hot flushes.